5-MeO-DMT Retreat: The Complete Guide For 2025
What Is 5-MeO-DMT?
What Is 5-MeO-DMT? Spiritual Use and Retreat Culture: 5-MeO-DMT is a type of psychedelic that participants take to experience non-duality. Many intend to work with 5-MeO so that they may experience a feeling of oneness with God and the entire universe. As a chemical, 5-MeO-DMT is found in numerous plants as well as toads native to North and South America.Aside from non-duality, there are several other descriptors that people who have worked with 5-MeO like to use.
Some describe the entire experience as an “ego death” due to the separation one feels from one’s self and merging with the infinite. At the end of the day, it’s really up to the individual to decide how they would like to interpret their 5-MeO experience.
History
Far from being a recent phenomenon, indigenous practitioners have experimented with 5-MeO-DMT for over 3,000 years. Initially, individuals consumed the medicine in the form of crushed seeds. The medicine was often integrated into spiritual ceremonies, too. The use of 5-MeO-DMT didn’t reach widespread notoriety until the 1950s.
This was prompted by the 1936 discovery and synthesis of the 5-MeO-DMT compound in a lab by two Japanese scientists. As a result, synthetic 5-MeO became far more reproducible, and thus, numerous psychonauts commenced experimentation. Many associate 5-MeO-DMT with toad medicine.
More specifically, they are referring to venom, which is extracted from the Sonoran desert toad. However, this discovery in toads is relatively recent compared to its usage synthetically or via plants. Unfortunately, the popularity of 5-MeO-DMT has led to a depletion of this toad’s population. We encourage retreat centers to avoid using toad venom for their 5-MeO-DMT and instead switch to synthetic or plant varieties in the interest of sustainability.
Common Myths
As with any psychedelic medicine, 5-MeO-DMT has come under fire from all angles ranging from open-minded but skeptical psychonauts to powerful governmental regulatory bodies. It’s hard for anyone to come up with an airtight scientific case for or against 5-MeO; the substance is banned in most western countries. That said, the limited amount of scientific studies conducted on this matter have indicated that the substance is rather beneficial to the individuals that take it.
“5-MeO Makes You Go Crazy”
In the vast majority of instances, 5-MeO-DMT is harmless. In our years of work with 5-MeO, we have never observed anyone who “went crazy” after taking the medicine. Perhaps this is because we employ a rigorous pre-screening process to filter out individuals we deem unsuitable for 5-MeO-DMT.
During our initial calls, we search for any psychiatric conditions that might prevent you from being a suitable candidate for 5-MeO-DMT. We also have candidates submit a saliva swab test to test for a propensity toward serotonin syndrome or any other conditions that make taking 5-MeO-DMT risky.
If we find you to be in any way an unsuitable candidate, we refund your deposit in full.We’ve turned very few people away over the years. In reality, 5-MeO is only dangerous to its users if they embark upon the journey alone. Therefore, you will increase your chances of having a good trip by having a well-trained and experienced facilitator assist you throughout. They can help set the stage for the 5-MeO-DMT experience and aid you in cases where you might need it, such as during energy blockages.
“5-MeO Is Addictive”
Like the magic mushroom and other psychedelic medicines, 5-MeO-DMT is not actually addictive. In fact, some individuals use 5-MeO-DMT to reduce addictive tendencies and other mental health disorders. This is because 5-MeO is a transformational experience. The objective is to transform your mental patterning, and retreat practitioners are the ones who help you achieve this no matter what your objective.
“I need MORE EXPERIENCE WITH PSYCHEDELICS”
Many people erroneously believe that you shouldn’t take 5-MeO-DMT unless you’ve had experience with psychedelic medicine in the past. There is no reason why this should be true. No psychedelic can somehow prepare you for 5-MeO-DMT. Many of our past retreat-goers report that 5-MeO was the first psychedelic that they ever took.
“5-MeO-DMT IS Nn-DMT”
Because both compounds have “DMT” in their name, they often get confused with one another. While their chemical structure is similar, your experience with the two drugs will be quite different. People who talk about DMT in casual conversation are almost always referring to Nn-DMT whereas 5-MeO-DMT goes by the name “5-MeO” or “the toad”.If you’ve taken DMT you’ll understand that the drug produces a vibrant visual experience.
This is a stark contrast to 5-MeO which we would say goes beyond the 5 senses and produces a feeling of non-duality. Moreover, 5-MeO is usually far more elating than DMT.